ACE inhibitor commonly causes which side effect due to bradykinin accumulation?

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Multiple Choice

ACE inhibitor commonly causes which side effect due to bradykinin accumulation?

Explanation:
Bradykinin accumulation due to ACE inhibition causes a dry cough. ACE normally degrades bradykinin, so blocking it lets bradykinin build up. That buildup can irritate airway sensory nerves and trigger a persistent cough, and it also raises the risk of angioedema. Other effects like hypotension, headache, or hyperglycemia aren’t driven by bradykinin accumulation in the same way, even though ACE inhibitors can cause BP changes. So the cough is the side effect most directly linked to bradykinin buildup.

Bradykinin accumulation due to ACE inhibition causes a dry cough. ACE normally degrades bradykinin, so blocking it lets bradykinin build up. That buildup can irritate airway sensory nerves and trigger a persistent cough, and it also raises the risk of angioedema. Other effects like hypotension, headache, or hyperglycemia aren’t driven by bradykinin accumulation in the same way, even though ACE inhibitors can cause BP changes. So the cough is the side effect most directly linked to bradykinin buildup.

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